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Table 2 Hypothetical audience segments and tailored implementation strategies

From: Using audience segmentation to identify implementation strategies to improve PrEP uptake among at-risk cisgender women: a mixed-methods study protocol

Segment name

Example audience segment description

Potential targeted implementation strategies

Implementation resource intensity

“Excited and Open”

Consider PrEP in scope of practice; open to prescribing to cis women; low knowledge about cis women specific needs for PrEP; perceived client population at moderate risk; high clinic-level support for PrEP for cis women

Centralizing educational materials to disseminate new data/best practices; provide implementation “how-to” guide for individual provider prescription

Low

“Needs a Nudge”

Does not consider PrEP in current scope of practice; some openness to prescribing; low levels of PrEP knowledge; perceive patients to be at moderate risk of HIV; moderate clinic-level support for PrEP for cis women

Provider level education about HIV risk and PrEP for cis women; provide implementation “how-to” guide for individual provider prescription; provide ongoing consultation; Identify and prepare implementation champions

Moderate

“HIV not a problem for women”

Does not consider PrEP in current scope of practice; not comfortable prescribing; low levels of PrEP knowledge; perceive patients to be at low risk of HIV; high clinic-level support for PrEP for cis women

Provider stigma reduction intervention; Provider level education about HIV among cis women; clinic-level implementation structure developed

High

“Not a Chance”

Does not consider PrEP in current scope of practice; not comfortable prescribing; low levels of PrEP knowledge; perceive patients to be at low risk of HIV; low clinic-level support for PrEP for cis women

Given low levels of provider and clinic-level support for PrEP for women, implementation efforts for this segment are unlikely to yield behavior change in providers. Thus, limited resources should be dedicated to other segments that have a higher likelihood of impact

Too high